Diabetic retinopathy
Conditions
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the retrospective cohort study: 1. Primary care patients in urban and rural areas diagnosed with T2DM from May 2014 to November 2025 (based on the 1999 WHO criteria); 2. Age 18–70 years, regardless of gender; 3. At least one follow-up visit with a follow-up duration of more than 6 months. Inclusion criteria for the prospective cohort study: 1. Collection of primary care patients diagnosed with T2DM in January 2026 (based on the 1999 WHO criteria); 2. Age 18–70 years, regardless of gender; 3. Voluntary participation and acceptance of health examinations, vision tests, non-mydriatic fundus photography, and blood sample collection as part of this study; 4. Participants sign a written informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the retrospective cohort study: 1. Presence of diabetic retinopathy (DR) at baseline; 2. Presence of other non-diabetic ocular diseases that may interfere with fundus examination results (such as glaucoma, cataract, age-related macular degeneration, non-diabetic hemorrhagic eye diseases, uveitis, retinal detachment, optic nerve diseases, or abnormalities in the ocular refractive media); 3. Concurrent acute diabetic complications, including diabetic ketoacidosis or hyperosmolar hyperglycemic state; 4. Other concomitant diseases that may affect glucose metabolism, such as acute infections, chemotherapy, or corticosteroid use; 5. Lack of follow-up data on diabetic retinopathy. Exclusion criteria for the prospective cohort study: 1. Patients with previously diagnosed diabetic retinopathy (DR); 2. Presence of other non-diabetic ocular diseases that may interfere with fundus examination results (such as glaucoma, cataract, age-related macular degeneration, non-diabetic hemorrhagic eye diseases, uveitis, retinal detachment, optic nerve diseases, or abnormalities in the ocular refractive media); 3. Concurrent acute diabetic complications, including diabetic ketoacidosis or hyperosmolar hyperglycemic state; 4. Other concomitant diseases that may affect glucose metabolism, such as acute infections, chemotherapy, or corticosteroid use; 5. Unwillingness to sign the informed consent form; 6. Unwillingness or inability to undergo regular follow-up visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diabetic retinopathy; | — |
Countries
China
Contacts
Public ContactHongyu Kuang
The First Affiliated Hospital of Harbin Medical University
Outcome results
None listed