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Analysis of organ-specific genomic characteristics and origin of plasma ctDNA in advanced colorectal cancer

Analysis of organ-specific genomic characteristics and origin of plasma ctDNA in advanced colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104365
Enrollment
Unknown
Registered
2025-06-16
Start date
2025-06-20
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Observation group:None

Sponsors

Characteristic Medical Center of Chinese People 's Armed Police Force(Tianjin University Integrative Medicine Center)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years (no upper age limit) ; 2.pathological diagnosis was colorectal adenocarcinoma ; 3.the location of tumor metastasis and the number of metastases can be clarified ; 4.tumor lesion tissue can be obtained by surgical resection or puncture ; 5.baseline blood samples can be obtained before treatment;6.PS score 0-1 points ; 7.informed consent can be obtained .

Exclusion criteria

Exclusion criteria: 1.Patients with familial hereditary tumors ; 2.other serious diseases that may affect follow-up and short-term survival ; 3.any social / psychological problems, etc., judged by the researcher is not suitable for patients to participate in this study ; 4.known history of allogeneic organ transplantation or allogeneic hematopoietic stem cell transplantation ; 5.patients who need antiviral therapy during the study ; 6.the researchers evaluated other situations that were not suitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
overall survival, OS;plasma ctDNA;Molecular phenotypic characteristics;

Secondary

MeasureTime frame
progression-free survival, PFS;

Countries

China

Contacts

Public ContactGuibing Ren

Characteristic Medical Center of Chinese People 's Armed Police Force(Tianjin University Integrative Medicine Center)

renguibing1972@163.com+86 158 2242 5938

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026