Patients undergoing tumor ablation surgery
Conditions
Interventions
Ci-profol:Ci-ropofol group
Profol:Propofol group
Sponsors
Lishui Central Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age >= 45 years, <= 80 years, gender limited; 2) Patients who received tumor ablation under CT guidance; 3) ASA grade of II~III; 4) BMI of 18 kg/m <= BMI<= 25 kg/m^2; 5) The estimated operation time was not more than 2 hours; 6) Be clear about, voluntarily participate in the study and sign the informed consent by himself or his family.
Exclusion criteria
Exclusion criteria: 1) Proposed to perform general anesthesia with endotracheal intubation; 2) The patient's SpO2 <= 95% after entering the room; 3) Patients with severe heart disease such as severe myocardial infarction within the past 6 months, heart failure within past 1 month, arrhythmias requiring treatment, angina pectoris, severe heart valve lesions, etc.; 4) Patients with severe respiratory insufficiency obstructive pulmonary disease, a history of bronchospasm requiring treatment within the past 3 months, respiratory tract infection within the past 2 weeks with obvious symptoms such as, expectoration, fever, nasal congestion, etc.; 5) Patients allergic to propofol or cyproterone; 6) Patients with schizophrenia, intellectual, mania, psychosis, long-term use of psychotropic drugs, drug addiction, history of cognitive dysfunction, etc.; 7) Patients considered unsuitable for in this experiment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 54/2000 Incidence of respiratory-related adverse events (respiratory depression, apnea, hypoxia);Incidence of adverse events related to the circulatory system (hypotension, arrhythmia); | — |
Secondary
| Measure | Time frame |
|---|---|
| Wake-up time;Time to successful induction of sedation/anesthesia;Nausea and vomiting occurrence and severity;Drug use situation;Sedation/anesthesia satisfaction evaluation; | — |
Countries
China
Contacts
Public ContactHao Cheng
Lishui Central Hospital
Outcome results
None listed