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Evaluation of epidural block technique (DPE) combined with programmed intermittent pulse (PIEB) in painless delivery

The Application of DPE in Labor Analgesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104357
Enrollment
Unknown
Registered
2025-06-16
Start date
2025-06-20
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain (pain occurring during labor)

Interventions

Group EP:Epidural block technology + programmed epidural intermittent pulse drug delivery technology
Group DPE:Epidural puncture and epidural block + programmed epidural intermittent pulse drug delivery technique

Sponsors

Xinyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 34 Years

Inclusion criteria

Inclusion criteria: 1.First-time mothers between the ages of 20-34. 2.single fetus, head position, gestational week between 37-42 weeks, in line with the indication of natural childbirth. 3.Cervical dilation of 2-5cm, with regular contractions at least every 5 minutes, and Visual Analogue Scale (VAS) when intraspinal analgesia is required. The baseline pain score was > 5 (0 = no pain, 10 = the most severe pain), voluntarily accepted labor analgesia, ASA grade I-II, and had no related contraindications to anesthesia. 4.maternal clinical data complete, and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.There are contraindications to epidural anesthesia, such as coagulation dysfunction, spinal deformity and so on; 2.there are serious comorbidities, such as hypertensive diseases during pregnancy, diabetes, etc. 3.The patient was converted to cesarean section and there were known fetal abnormalities. 4.Allergic to or dependent on analgesic drugs. 5.Cognitive, communication or psychiatric disorders. 6.Body mass Index (BMI) >35kg/m^2. 7.Have used opioid drugs or other analgesic drugs or sedatives within 4 hours before requesting intraspinal labor analgesia.

Design outcomes

Primary

MeasureTime frame
The time required to achieve effective analgesia after initial administration;Neonatal Apgar score;Prolonged deceleration (PD) occurs;

Secondary

MeasureTime frame
Sufentanil daaczzosage;Progress of labor;the time to first patient controlled epidural analgesia;Serum pain substance;Dosage of ropivacaine;Maternal satisfaction;Complications and adverse reactions;PCEA actual number of compressions;Occurrence of postpartum depression;Incidence of asymmetric block and sacrococcygeal block insufficiency;The effective analgesic rate is achieved after the first dose;The incidence of motor block;

Countries

China

Contacts

Public ContactMei Lei

Xinyang Central Hospital

meileiaijia2009@163.com+86 376 666 7445

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026