Perioperative atrial fibrillation
Conditions
Interventions
Normal saline group:Spray 10 ml of normal saline onto the surface of the visceral pleura
Lidocaine group:Spray 10 ml of 2% lidocaine onto the surface of the dirty pleura
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Participants undergoing thoracoscopic lobectomy/segmentectomy under elective general anesthesia; 2. The participants' ages range from 45 to 75 years old; 3. ASA Grade II - III; 4. Be able to comply with the requirements of the research visit plan and other programs; 5. Sign the informed consent form and voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: 1. Participants with a previous history of atrial fibrillation; 2. Participants who are currently taking antiarrhythmic drugs such as beta-blockers, calcium channel blockers or digoxin; 3. Participants with contraindications to lidocaine use (For example: lidocaine allergy); 4. Participants with severe systemic diseases; 5. Participants who refused to participate in this trial; 6. Participants with severe liver and kidney dysfunction; 7. Participants with severe cardiovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of atrial fibrillation during the perioperative period of thoracic surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic analysis;The consumption of vasoactive drugs during the operation;The incidence of atrial fibrillation within 3 days after the operation;The length of hospital stay of the patient;Postoperative VAS score;PCIA consumption and cumulative number of compressions;Incidence of other adverse reactions;C-reactive protein;Interleukin-6;Neutrophil-to-lymphocyte ratio;N-terminal pro-brain natriuretic peptide;Cardiac troponin I;Electrolyte levels: serum magnesium; serum potassium; serum sodium; | — |
Countries
China
Contacts
Public ContactZhongmeng Lai
Fujian Medical University Union Hospital
Outcome results
None listed