neurogenic respiratory failure
Conditions
Interventions
Experimental group :nothing
Control group:nothing
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The age of 18 years old and above, male or female; 2.Craniocerebral injury, intracranial infection, cerebrovascular disease, peripheral nerve or muscle disease and other neurogenic diseases leading to ventilator withdrawal difficulties were diagnosed as neurogenic respiratory failure; 3.Need to rely on ventilators to maintain respiratory function, continuous use of ventilators for more than 48 hours; 4.No serious heart, liver, kidney and other organ dysfunction, no serious infection, bleeding, tumor and other complications; 5.No contraindications or allergic reactions to ultrasound or shear-elastography; 6.Volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.The patients with serious lung disease or cardiovascular disease; 2.Respiratory failure caused by other causes such as lung disease, thoracic deformity, etc.; 3.There are structural or functional abnormalities of the diaphragm or other respiratory muscles, such as diaphragmatic hiatus hernia, muscular dystrophy, etc.; 4.There are factors that affect the results of shear elastography, such as ascites, pneumothorax, pleural effusion, etc; 5.Vital signs fluctuate, may be further aggravated life-threatening; 6.Serious adverse events occurred during the study period, such as cardiac arrest, respiratory arrest, shock, etc. 7.During the study period, the participant voluntarily withdrew or was terminated by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| shear wave velocity;Young modulus; | — |
Countries
China
Contacts
Public ContactWang Zhiqiang
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed