None listed
Conditions
Interventions
Group D: Stellate Ganglion Block (SGB) with Intranasal Dexmedetomidine:Stellate ganglion block (SGB) combined with intranasal dexmedetomidine spray
Group D: Stellate Ganglion Block (SGB) with Intranasal Dexmedetomidine:Stellate ganglion block combined with intranasal spray of isovolumic saline
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=65 years, BMI 18.5–28 kg/m², and ASA physical status I–III; 2.Scheduled for elective laparoscopic resection of gastrointestinal malignancies under general anesthesia; 3.Surgical duration <=4 hours; 4.Voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Preoperative Pittsburgh Sleep Quality Index (PSQI) score >5; 2.Long-term or recent continuous use of opioids or psychoactive medications; 3.Diagnosis of obstructive sleep apnea-hypopnea syndrome (OSAHS); 4.Preoperative cognitive impairment or inability to communicate; 5.Severe trauma, infection, or other pathologies at the puncture site/surgical access route; 6.Upper respiratory tract infection within the past 2 weeks, or presence of respiratory cysts, tumors, or polyps. 7.Contraindications or allergies to related study medications; 8.Concurrent participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the postoperative VAS score, HADS score, serological markers, and the incidence of adverse events within three days after surgery;Leeds Sleep Evaluation Questionnaire (LSEQ) score and Objectively measured sleep parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serological markers;Incidence of adverse events within the first 3 postoperative days;Postoperative VAS scores;Postoperative Hospital Anxiety and Depression Scale score; | — |
Countries
China
Contacts
Public ContactZhong Maolin
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed