Knee Osteoarthritis.
Conditions
Interventions
Control group (sham stimulation group):(1) Health education
(2) aerobic exercise based on the FITT principle
(3) Muscle strength training
(4) sham stimulus
Experimental group (rTMS stimulation group):(1) Health education
(2) aerobic exercise based on the FITT principle
(3) Muscle strength training
(4) In the experimental group, participants received a 15
Sponsors
Honghui Hospital, Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meets the KOA diagnostic criteria established by EULAR 2. Age > 40 years 3. Persistent or recurrent pain with a duration of more than 3 months 4. Brief Central Sensitization Inventory (CSI-9) score > 10 points 5. Patients sign the informed consent form and actively cooperate with the treatment
Exclusion criteria
Exclusion criteria: 1. Previous knee or hip arthroplasty 2. In the acute phase of a disease, such as unstable heart disease, systemic infection, and high fever, leading to difficulty and discomfort in testing 3. Pregnant women, or individuals with cognitive impairment 4. Presence of contraindications for TMS use, such as a history of neurological diseases and structural brain injury, presence of a cardiac pacemaker, increased intracranial pressure, metal or implanted devices within the skull, cochlear implants, history of epilepsy, and metabolic abnormalities 5. Use of drugs that may affect cortical electrical activity (anticonvulsants, antidepressants, or antipsychotics)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale;Pressure Pain Thresholds;Movement-evoked Pain Index;Central Sensitization Inventory,CSI-9;Resting Motor Threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Countries
China
Contacts
Public ContactXifang Liu
Honghui Hospital, Xi'an Jiaotong University
Outcome results
None listed