Small cell lung cancer
Conditions
Interventions
Neoadjuvant Chemotherapy+Immunotherapy group:None
Sponsors
The Army Characteristic Medical Center of the People's Liberation Army of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 80 years old; 2.Pathologically confirmed small cell lung cancer (SCLC); 3.SCLC with clinical stage I-III (referring to the 8th edition of the AJCC); 4.Received neoadjuvant chemotherapy for 2 cycles or more before surgery, or neoadjuvant treatment with a combination of immune checkpoint inhibitors (PD-1 or PD-L1 inhibitors) and chemotherapy; 5.Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1;
Exclusion criteria
Exclusion criteria: 1. Incomplete imaging data, for example, there is only one imaging assessment; 2. Previously received anti-tumor treatments, such as radiotherapy, interventional therapy, or pharmacotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pCR rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| TME analysis;Downstaging rate of tumor stage;R0 resection rate;Incidence of grade >=3 adverse events;MPR rate;Objective response rate, ORR;Event free survival, EFS; | — |
Countries
China
Contacts
Public ContactLi Li
The Army Characteristic Medical Center of the People's Liberation Army of China
Outcome results
None listed