Morbid Obesity
Conditions
Interventions
Experimental Group:Received 6 months of lifestyle intervention + 3 months of GVR-100 gastric volume microsphere treatment
Control group:Received 6 months of lifestyle intervention
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 16-65 years old; 2. Voluntarily participate in this study, with clear awareness, able to understand and cooperate with lifestyle managers. 3. Patients who have undergone weight loss surgery and meet one of the following conditions: (1) After the patient's weight drops to the lowest point, the% EWL increases by more than 25%, or the BMI increases by more than 5, or the weight increases by more than 10 kg; (2) The patient's% EWL changes from>50% to<50%, or their BMI is greater than 35; (3) After the patient's weight drops to the lowest point, the weight gain is greater than 20% of the maximum preoperative weight loss. (4) After the patient's weight drops to the lowest point, their weight gain exceeds 10% of their preoperative weight
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding female; 2.Patients refused to sign an informed consent form; 3.Patient had a history of psychiatric illness or severe cognitive impairment; 4.Patients with severe organ dysfunctions who cann't take part in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total weight loss rate over three months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total weight loss rate over six months;Waist circumference at three and six months;Hip circumference at three and six months;Body Mass Index at Three and Six Months;Blood pressure at three and six months;Fasting blood glucose levels at three and six months;Glycated hemoglobin at three and six months;Insulin resistance index at three and six months;Blood lipid at three and six months;Serum insulin levels at three and six months;Liver function at three and six months;Renal function at three and six months;Uric acid levels at three and six months; | — |
Countries
China
Contacts
Public ContactShaozhuang Liu
Qilu Hospital of Shandong University
Outcome results
None listed