Major Depressive Disorder
Conditions
Interventions
Control group:None
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: MDD enrolment criteria: 1.Meet the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria for depression;2.Age 18-65 years old; 3.No physical disease;4.No substance abuse or dependence; 5.No suicidal thoughts or behaviors. HC enrolment criteria:1.No history of mental illness; 2.Age 18-65 years old; 3.Not pregnant or breastfeeding.
Exclusion criteria
Exclusion criteria: 1. Exclude persons who meet the DSM-5 diagnostic criteria for schizophrenia, schizoaffective disorder, mental retardation, generalized developmental disorder, delirium, dementia, memory impairment, or other cognitive impairment. 2. Exclude patients with serious unstable physical diseases, diagnosed diabetes, thyroid disease, hypertension, heart disease, etc. 3. Exclude patients with a history of epilepsy, except febrile convulsions. 4. Exclude pregnant or lactating women, or those planning pregnancy. 5. Exclude those who have contraindications with MRI scanning. 6. Exclude those who have had MECT within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interoception;Major Depressive Disorder;fMRI;Neurotransmitter; | — |
Countries
China
Contacts
Public ContactWenliang Wang
Wuxi Mental Health Center
Outcome results
None listed