Lung cancer and lung nodules
Conditions
Interventions
C Group:Administer 10ml of normal saline
E1 Group:Administer 0.3 mg/kg of esketamine.
E2 Group:Administer 0.5 mg/kg of esketamine.
Sponsors
Hainan Affiliated Hospital of Hainan Medical University(Hainan General Hospital )
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients undergoing thoracoscopic surgery at the People’s Hospital of Hainan Province from January 2025 to December 2026 were selected, with ASA I - II classification, aged 18 - 65 years, and a body mass index (BMI) of 18.5 - 27.9 kg/m^2, who voluntarily participated in the study
Exclusion criteria
Exclusion criteria: Patients with cognitive or language deficits impairing communication and cooperation, psychiatric disorders, intracranial hypertension, or glaucoma were excluded. Those with ischemic heart disease, poorly controlled hypertension (resting SBP >180 mmHg or DBP >100 mmHg), drug/alcohol use, ketamine addiction, difficult airway, reactive airway disease, acute upper respiratory infection, or high aspiration risk were also excluded. Additionally, patients allergic to ketamine or etomidate, with hyperthyroidism, pregnant or breastfeeding women, those in clinical trials within the past 3 months, and those declining study participation were ineligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presure;Heart rate;Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time;Postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactJiale Li
Hainan Affiliated Hospital of Hainan Medical University(Hainan General Hospital )
Outcome results
None listed