Emergency cesarean section
Conditions
Interventions
Intrathecal anesthesia group:None
Sponsors
Nanjing Jiangning Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Gestational age >= 34 weeks, singleton pregnancy, emergency cesarean section (excluding elective surgery).
Exclusion criteria
Exclusion criteria: (1) Maternal-related confounding factors: Pregnancy complications: preeclampsia (systolic blood pressure >= 160 mmHg or proteinuria >= 5g/24h), gestational diabetes (abnormal OGTT and requiring insulin treatment); respiratory system diseases: COPD (GOLD classification >= II), acute asthma exacerbation (requiring bronchodilator treatment); circulatory system abnormalities: persistent hypotension (MAP 180 mmHg); hematological disorders: severe anemia (Hb 1.5 or platelets 95th percentile. (3) Labor-related interference factors: Abnormal labor: active phase arrest (cervical dilation stasis >= 4h), prolonged second stage of labor (primipara >3h / multipara >2h); obstetric interventions: emergency cesarean section (decision to delivery time = 3 times with abnormal fetal heart rate. (4) Drug interference factors: Oxytocin use: infusion rate >20 mU/min for more than 1 hour; tocolytics: prolonged intravenous administration of ritodrine, sublingual nitroglycerin; analgesics: non-study protocol opioids (pethidine >50 mg). (5) Specimen quality control: Improper timing of collection: non-standard blood collection time window (30-60 minutes after epidural administration); specimen handling defects: exposure to air for >2 minutes, failure to use heparinized collection tubes; testing delay: failure to conduct blood gas analysis within 15 minutes after blood collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Types of anesthetic drugs;Anesthetic drug dosage;Anesthesia operation time;Maternal hemodynamics;Umbilical cord blood pH;Cord blood lactate level;Apgar score for newborns;Neonatal resuscitation needs;Early complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;BMI;Comorbidities;Surgical urgency classification; | — |
Countries
China
Contacts
Public ContactGuo Jidong
Nanjing Jiangning Hospital
Outcome results
None listed