Myoma of uterus
Conditions
Interventions
Bupivacaine liposomal group:20ml/133mg liposome bupivacaine on each side was used to perform anterior and bilateral block of quadrate lumboes muscle superior arcuate ligament
Bupivacaine group:20ml/50mg bupivacaine hydrochloride (0.25%) on each side was used for anterior and bilateral block of quadrate lumbosi muscle of arcuate ligament
Sponsors
Chengdu Fifth People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18~75 years old; 2.BMI 16~29 kg/m^2; 3.ASA I.~II level; 4. Elective laparoscopic total hysterectomy.
Exclusion criteria
Exclusion criteria: 1. Allergy to anesthetic drugs in the study protocol; 2. Patients with infection at the puncture site; 3. Obvious abnormality of coagulation function; 4. Lumbar and abdominal radiotherapy or history of surgery; 5. Neuromuscular disease or psychiatric disease; 6. Severe liver and kidney insufficiency; 7. Refusal to undergo nerve block or refusal to use an intravenous analgesic pump; 8. Inability to understand and communicate; 9. Long-term use of sedative and analgesic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40 after 24h surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-40 1 day before surgery;QoR-40 after 48h surgery;QoR-40 after 72h surgery;Resting and exercise VAS scores at 12h, 24h, 48h and 72h after surgery;Intraoperative analgesic use;Number of analgesic remedies;Intraoperative vasoactive drug use;Operation duration;First time out of bed;Gastrointestinal function recovery time;Discharge time (Surgery - Discharge);Nausea and vomiting, skin itching, drowsiness, vertigo and other adverse reactions and nerve block complications occurred; | — |
Countries
China
Contacts
Public ContactYi Mingling
Chengdu Fifth People's Hospital
Outcome results
None listed