Persistent atrial fibrillation
Conditions
Interventions
Experimental group:None
Control group:None
Sponsors
Affiliated Qingyuan Hospital, Guangzhou Medical University,Qingyuan People's Hospital;
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Experimental group: (1) meet the criteria for continuous diagnosis and be diagnosed in our hospital; (2) Radiofrequency ablation treatment by our hospital; (3) No history of allergy to the drugs related to this study; (4) Age 18~70 years old; (5) Cardiac function grade: NYHA classification is I.~III.; (6) simultaneous treatment of metoprolol sustained-release tablets and amiodarone tablets; 2. Control group: (1) meet the criteria for continuous diagnosis and be diagnosed in our hospital; (2) Radiofrequency ablation treatment by our hospital; (3) No history of allergy to the drugs related to this study; (4) Age 18~70 years old; (5) Cardiac function grade: NYHA classification is I.~III.; (6) Use only amiodarone tablets for treatment.
Exclusion criteria
Exclusion criteria: 1. Severe malignant tumors, hyperthyroidism, coagulation insufficiency; 2. Rheumatic valvular heart disease, pulmonary heart disease; 3. Cardiac function grade IV; 4. Liver and kidney insufficiency (aspartate aminotransferase or alanine aminotransferase= 3 times the upper limit of normal; Creatinine >3.5mg/dl or endogenous creatinine clearance <30 ml/min), electrolyte disorders; 5. Combined with bronchospasm; 6. Allergy to the drugs used in this study; 7. Heart rate less than 60 beats/min; 8. Have a new myocardial infarction; 9. Have a history of COPD; 10. Have a severe infection; 11. Thrombocytopenia (platelet <=80×10^9 /L, or with anticoagulation contraindications); 12. History of surgery in the past 3 months; 13. Pregnant women; 14. Life expectancy is less than 1 year; 15. Hospital transfer, loss to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atrial fibrillation;Atrial flutter;Atrial tachycardia; | — |
Countries
China
Contacts
Public ContactXiaojian Liu
Qingyuan Hospital Affiliated to Guangzhou Medical University
Outcome results
None listed