heroin addiction
Conditions
Interventions
rTMS group:Repetitive transcranial magnetic stimulation (true versus sham stimulation)
tACS group:Transcranial alternating current stimulation (true versus sham stimulation)
Sponsors
School of Psychology, Northwest Normal University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Heroin addict with positive urine test results for opioids, negative urine test results for methamphetamine and other drugs, and assessed by an addiction psychiatrist at a drug rehabilitation hospital using a stereotyped clinical interview with DSM-5, no mixed drug use (i.e., heroin only), and no hallucinations or acute withdrawal symptoms; 2. Not receiving any form of treatment, including medication and non-invasive brain stimulation, no mixed drug use (i.e., heroin only), no hallucinations or acute withdrawal symptoms, no history of psychiatric illness or family history, such as schizophrenia and bipolar disorder; 3. Male health control group recruited through community advertising, with no history of alcohol or substance abuse disorder, psychiatric disorder, and cardiovascular disease; 4. Both groups of subjects were right-handed, and their visual acuity was normal or corrected. Screening criteria for the intervention include: 1. Do not mix new synthetic drugs such as methamphetamine, cocaine, and ephedra except heroin; 2. No neurological, cardiovascular, or other diseases; 3. No metallic foreign bodies or medical devices implanted in the body; 4. No acute physical or mental illness; 5. Willingness to overcome heroin use; 6. No hallucinations or acute withdrawal symptoms.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: Heroin addicts included in this study were excluded if they suffered from any serious physical illness (e.g., stroke, epilepsy, cranial trauma), or had a neurologic disorder such as an Axis I disorder (e.g., depression, bipolar disorder, schizophrenia) that met the DSM-5 criteria, or if there was a history of psychiatric illness or family history. Exclusion Criteria for Intervention: Has been treated with substitute medication such as substitution methadone after withdrawal, has experienced hallucinations or acute withdrawal symptoms within the previous week, has a history of cranial trauma, stroke, or epilepsy, has significant physical disability and infectious disease, has a metallic medical device implanted in the body, and has received rTMS or transcranial direct current stimulation treatment previously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Craving;Indicators of brain function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaire standardized scores;Behavioral indicators; | — |
Countries
China
Contacts
Public ContactXiaobin Ding
School of Psychology, Northwest Normal University
Outcome results
None listed