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The effect of using probiotics before surgery on postoperative complications, inflammation and nutritional status in patients with gastrointestinal tumours.

The effect of using probiotics before surgery on postoperative complications, inflammation and nutritional status in patients with gastrointestinal tumours.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104255
Enrollment
Unknown
Registered
2025-06-13
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer, colorectal cancer

Interventions

Sponsors

The Second Hospital of Lanzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18–80 years; 2) Diagnosed with primary gastrointestinal tumors by histopathology; 3) Proposed to undergo laparoscopic or open radical gastrointestinal tumors surgery with R0 resection; 4) Preoperative liver and renal function indexes (ALT, AST, Cr and BUN) were within the normal reference range.

Exclusion criteria

Exclusion criteria: 1) A combination of perforation, obstruction or active bleeding requiring emergency surgery. 2) Use of antibiotics, probiotic preparations or active infections within four weeks before enrolment. 3) A combination of autoimmune diseases, a history of malignancy or being pregnant/lactating. 4) The presence of contraindications to surgery or distant metastases (M1 stage).

Design outcomes

Primary

MeasureTime frame
Short-term infectious complications;Neutrophil-to-Lymphocyte Ratio;

Secondary

MeasureTime frame
The time of first stool after surgery;Duration of postoperative antibiotic use;Length of postoperative hospital stay;Albumin-to-globulin ratio;Prognostic Nutritional Index;Microbiota in stool;

Countries

China

Contacts

Public ContactMao Jie

The Second Hospital of Lanzhou University

maojie2004003@sina.com+86 136 3939 8741

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026