Type 2 diabetes
Conditions
Interventions
Experimental group:A 12-week exercise intervention program was administered under the supervision of exercise physiology staff
Control group:None
Sponsors
Fujian Normal University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Have type 2 diabetes; 2. Self-reported lack of regular exercise habits; 3. Conscious and able to voluntarily participate in exercise interventions; 4. Sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment; 2. Have serious comorbidities or complications, such as heart failure, autonomic neuropathy and stroke; 3. Have musculoskeletal diseases that cause motor dysfunction; 4. Have a history of cancer; 5. Allergy to nitroglycerin; 6. Have low blood pressure; 7. Have glaucoma; 8. Have end-stage renal disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nitroglycerin-mediated dilation;Myocardial work; | — |
Secondary
| Measure | Time frame |
|---|---|
| FBG(fasting blood-glucose);Insulin levels;Echocardiography;24-hour ambulatory electrocardiogram;24-hour ambulatory blood pressure;Cardiopulmonary exercise test;Speckle tracking imaging;Blood pressure;Flow-mediated dilation;Pulse wave;NO;ET-1;Blood lipid ;Glycated hemoglobin;2-hour postprandial blood glucose;Epinephrine;Norepinephrine;Cortisol;5-HT;Dopamine;GABA;TNF-a;IL-6;IL-10;Cardiac troponin I;NT-proBNP;Myo;Creatine kinase;CK-MB;SOD;MDA;CRP;ECG;Body composition;Waist-to-Hip Ratio;Skinfold thickness;Fat thickness;BMI;ROS;Nrf2;NLRP3;Sirt1;FOXO3;24-hour activity behavior;Energy metabolism test;Glucose tolerance test; | — |
Countries
China
Contacts
Public ContactDan Wang
Fujian Normal University
Outcome results
None listed