Ovarian cancer
Conditions
Interventions
Serous high-grade ovarian cancer:None
Sponsors
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Female patients aged 18 years or above; 2. Patients with histologically confirmed primary high-grade serous ovarian cancer, fallopian tube cancer or primary peritoneal cancer (untreated); 3. Willing to provide archived tissue samples or fresh tissue samples; 4. Only accepting surgical samples (the samples will undergo formalin fixation for 12 to 72 hours and subsequent paraffin embedding (FFPE) treatment); 5. Able to provide corresponding medical history (tumor stage); 6. Willing to undergo FRa and other tests and able to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Non-primary ovarian tumors (ovarian metastatic tumors); 2. Patients with endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma or sarcoma tissue, or mixed tumors containing any of the above histological types, or low-grade / borderline ovarian tumors; 3. Patients with only tumor biopsy specimens; 4. Specimens prepared before March 2021.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the expression intensity of FRa in tissue specimens of high-grade serous ovarian cancer patients in China (separately analyze the expression ratios of FRa at 0, 1+, 2+, and 3+).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analyze the expression intensity of FRa in tissue specimens of patients with different pathological stages;Match the consistency of the expression intensity of FRa in the samples. Matching samples are defined as samples of the same patient at different time points, such as samples from two surgeries of the; | — |
Countries
China
Contacts
Public ContactCao Dengfeng
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed