The effect of preoperative acute sleep deprivation on postoperative memory consolidation dysfunction
Conditions
Interventions
preoperative normal sleep group:None
Preoperative acute insomnia group:None
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years old; 2. American Society of Anesthesiologists (ASA) classification I-III; 3. BMI 18.5-27.9 kg/m^2; 4. Patients will undergo elective thoracoscopic wedge resection, segmentectomy, or lobectomy of the lungs; 5. Patients who are willing to participate in the trial and have provided written consent. consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of mental and long-term use of psychotropic drugs; 2. Patients with severe language, hearing, and visual impairments; 3. Preoperative Mini Mental State Examination (MMSE) score5; 5. Patients with acute gastroenteritis, constipation, and diarrhea in the past month; 6. Patients who have taken antibiotics in the past month; 7. People with metabolic diseases and autoimmune diseases such as diabetes, irritable bowel syndrome, inflammatory bowel disease, etc; 8. Patients with previous thyroid diseases; 9. Patients with special dietary habits (such as vegetarians, carnivores, low carbohydrate eaters, etc.); 10. Smokers and alcoholics; 11. Pregnant or lactating individuals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| memory; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal microbiota;Metabolites of intestinal bacteria in serum;Serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactTianzuo Li
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed