Endometriosis and Endometriosis-Associated Ovarian Carcinoma
Conditions
Interventions
Gold Standard:Pathological Diagnosis
Index test:In this study, the "Exosomal Ovarian Cancer Auxiliary Diagnostic Kit (Chemiluminescence Method)" (OCS) kit was used for sample detection
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Females aged >=18 years; 2. Nitial diagnosis of endometriosis or EAOC based on clinical presentation and imaging findings (including transvaginal ultrasound and MRI), with surgical indications; 3. Consent to surgical treatment and availability of postoperative ovarian pathological diagnosis; 4. Sufficient specimens for serum marker testing; 5. Voluntary participation in this study with signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women;?; 2. Patients who have previously undergone surgery with available ovarian histopathological examination results;?; 3. Confirmed cases of recurrent ovarian carcinoma;?; 4. Patients receiving chemotherapy or pelvic radiotherapy within 6 months prior to sample collection;?; 5. Concurrent primary malignancies;?; 6. Contraindications to surgical evaluation or inability to obtain ovarian surgical pathology information;?; 7. Specimens non-conforming to collection/preservation requirements, or contaminated/suspected contaminated samples.?;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian Cancer Score;OCS differentiates the performance of EAOC from benign masses in endometriosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| OCS diagnoses performance in early EAOC;OCS differentiates between different types of endometrium Performance of heterotopia and different types of EAOC; | — |
Countries
China
Contacts
Public ContactYang Xiang
Peking Union Medical College Hospital
Outcome results
None listed