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Construction and validation of a diagnostic model for pulmonary thromboembolism based on plain chest CT radiomics

Construction and validation of a diagnostic model for pulmonary thromboembolism based on plain chest CT radiomics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104186
Enrollment
Unknown
Registered
2025-06-12
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary thromboembolism

Interventions

Index test:Chest plain CT

Sponsors

The Second Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.The current diagnosis represents the first episode of the disease; 2.Non-contrast chest CT and pulmonary artery phase contrast-enhanced CT were performed within 1 day after the initial onset; 3.At least one non-contrast chest CT scan was conducted within 1 year prior to the first episode; 4.Complete clinical data are available; 5.Willing and able to participate in the study, capable of signing informed consent, and demonstrating good compliance.

Exclusion criteria

Exclusion criteria: 1.Incomplete clinical or imaging data; 2.Poor image quality unsuitable for diagnostic evaluation; 3.Difficulty in delineating the region of interest (ROI); 4.Severe pulmonary consolidation; 5.Other types of pulmonary embolism such as tumor embolism, amniotic fluid embolism, fat embolism, or air embolism; 6.Participation in other drug clinical trials or discontinuation of investigational drugs for less than 3 months; 7.Patients unable to cooperate with study-related examinations or unwilling to provide informed consent.

Design outcomes

Primary

MeasureTime frame
CT of the Chest;Accuracy;Sensitivity;Specificity;

Secondary

MeasureTime frame
Demographic information;D-dimer;NT-proBNP;Troponin;Wells Score;Caprini Score;Pauda Score;Lower Extremity Venous Thrombosis Status;

Countries

China

Contacts

Public ContactYixin Lian

The Second Affiliated Hospital of Soochow University

lynelian@163.com+86 189 6211 3308

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026