Carotid artery stenosis
Conditions
Interventions
Control group:Conventional Eversion Carotid Endarterectomy
Experimental group:Self-Modified Eversion Carotid Endarterectomy
Sponsors
The Second affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
No minimum to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with carotid artery stenosis degree greater than 70% through CT angiography (CTA) or digital subtraction angiography (DSA); 2. Patients diagnosed by CTA or DSA with carotid artery stenosis degree greater than 50%, and who have experienced ipsilateral cerebral ischemic events in the past six months, such as recurrent TIA attacks; 3. Age under 85 years old; 4. The subjects and their families voluntarily sign a surgical informed consent form.
Exclusion criteria
Exclusion criteria: 1. Asymptomatic patients with carotid artery stenosis less than 70%, or symptomatic patients with carotid artery stenosis less than 50%; 2. Patients with complete occlusion of the carotid artery; 3. Known allergies or contraindications to contrast agents, heparin, antiplatelet drugs, or anesthetics; 4. Imaging examination suggests hemorrhagic transformation after cerebral infarction; 5. Ischemic stroke not caused by carotid artery; 6. The overall condition is poor, with severe infections, low blood volume, or hypotension that cannot tolerate general anesthesia surgery; 7. Life expectancy is less than 2 years; 8. Patients and their families refuse to participate in clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ipsilateral carotid artery restenosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total complication rate during the perioperative period.;Carotid artery clamping time during surgery;Improvement in postoperative cerebral ischemic symptoms.;Postoperative blood pressure stability (systolic and diastolic blood pressure).;Rate of patients requiring antihypertensive medication to control blood pressure after surgery;Incidence of postoperative bleeding-related complications;Postoperative sensitivity of the carotid body ventilatory reflex; | — |
Countries
China
Contacts
Public ContactJiehua Qiu
The Second affiliated Hospital of Nanchang University
Outcome results
None listed