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Efficacy evaluation of closed triple inhalation preparation in acute exacerbation of chronic obstructive pulmonary disease: a multicenter, prospective and real-world study

Efficacy evaluation of closed triple inhalation preparation in acute exacerbation of chronic obstructive pulmonary disease: a multicenter, prospective and real-world study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104172
Enrollment
Unknown
Registered
2025-06-12
Start date
2025-06-30
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease (COPD)

Interventions

Budgefu inhalation aerosol group:None

Sponsors

Shandong Provincial Hospital Affiliated to Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of COPD and AECOPD in the 2025 GOLD Guidelines; 2. There was a pulmonary function and bronchodilation test before joining the group; 3. At the time of enrollment, it was a mild to moderate acute exacerbation period.

Exclusion criteria

Exclusion criteria: The patient had previous diagnosis and treatment of asthma; Respiratory failure (pao 2 < 60 mmhg) was present at admission; Complicated with serious pulmonary heart disease, heart failure and other important diseases; Patients with large area and sub-large area pulmonary embolism; Women of childbearing age who are currently pregnant or breastfeeding; Have received immunosuppressive therapy or participated in other clinical researchers 3 months before joining the group.

Design outcomes

Primary

MeasureTime frame
Pulmonary function;Tracheal intubation rate;Hospitalization time and hospitalization expenses;Hematological index;

Secondary

MeasureTime frame
Dyspnea graded;COPD Assessment ;

Countries

China

Contacts

Public ContactSun Jian

Shandong Provincial Hospital Affiliated to Shandong First Medical University

sunjiansph@163.com+86 158 6660 2183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026