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Effect of water-assisted colonoscopy combined with water-soluble menthol on the antispasmodic effect of colonoscopy

Effect of water-assisted colonoscopy combined with water-soluble menthol on the antispasmodic effect of colonoscopy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104168
Enrollment
Unknown
Registered
2025-06-12
Start date
2025-01-27
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Menthol Group:During intubation, first instill 100 ml of 0.8% menthol solution.
Water Group:During intubation, first instill 100 ml of Normal Saline.

Sponsors

Lishui Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. Have indications for colonoscopy screening, surveillance, or diagnosis; 3. Outpatients or inpatients who have the capacity and agree to provide informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with known severe intestinal stenosis that makes intubation difficult; 2. Patients who have not undergone bowel preparation or whose preparation is inadequate; 3. Allergy to menthol; 4. Patients for whom intubation to the ileocecal valve is not required; 5. Patients with known adenomas or polyps; 6. Patients with a history of colorectal resection surgery; 7. Pregnant or breastfeeding women; 8. Patients with severe coagulation disorders or hemodynamic instability; 9. Patients in poor general condition who cannot tolerate colonoscopy (American Society of Anesthesiologists [ASA] physical status classification of Grade III or above); 10. Patients who are unable to sign the informed consent form or who withdraw midway.

Design outcomes

Primary

MeasureTime frame
Spasm Score (Antispasmodic Effectiveness Rate);

Secondary

MeasureTime frame
Adenoma Detection Rate (ADR);Examination Comfort (The Gloucester Comfort Scale);Insertion Time;

Countries

China

Contacts

Public ContactBin Ye

Lishui Central Hospital

408252097@qq.com+86 138 5707 8092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026