Traumatic Optic Neuropathy
Conditions
Interventions
Group 2:Endonasal Transnasal Optic Nerve Decompression
Group 4:Transcranial Optic Nerve Decompression (pterional approach)
Group 1:Steroid Pulse Therapy
Group 3:Transcranial Optic Nerve Decompression (supraorbital approach)
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
14 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients with monocular traumatic optic neuropathy; 2.The age range of the subjects is 14 to 70 years old (including 14 and 70 years old); 3.Consciousness with a GCS score of 12 or above;
Exclusion criteria
Exclusion criteria: 1.Global injury; 2.Presence of optic nerve injury outside the optic canal; 3.Pregnant or breastfeeding; 4.Individuals with cognitive or behavioral issues who are unable to cooperate in completing relevant examinations and follow-up work; 5.Participate in other clinical studies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of Visual Acuity 6 months after treatment;Fractional anisotropy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of mean deviation one week and 6 months after treatment;Changes of mean deviation one week and 6 months after treatment;Radial dispersion rate;Axial dispersion rate;Diffusion tensor magnetic resonance examination - mean diffusivity;Pattern standard deviation;Changes of Visual Acuity one week after treatment; | — |
Countries
China
Contacts
Public ContactChenlong Liao
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed