Upper gastrointestinal lesions <= 2 cm
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.The initial diagnosis was gastric and esophageal lesions (early cancer, intraepithelial neoplasia, submucosal tumors) with a lesion diameter <=2 cm, all of which were solitary and supported by pathological or endoscopic ultrasound evidence. 2.Patients aged under 65, with a body mass index (BMI) of 18.5 to less than 27.9. 3.Patients with an American Society of Anesthesiologists (ASA) physical status classification of I to III. 4.Patients who have signed an informed consent form, agreeing that their clinical data may be used for future research.
Exclusion criteria
Exclusion criteria: 1.Patients with serum albumin below 35 g/L or hemoglobin below 90 g/L. 2.Patients with bleeding-related risks (taking oral antiplatelet drugs or anticoagulants). 3.Patients who need additional surgical treatment after non-curative ESD. 4.Patients with active gastric ulcers or bleeding, or those who have had gastric bleeding or perforation after using nonsteroidal drugs. 5.Patients with severe heart disease and pulmonary disease. 6.Patients with peripheral vascular or cerebrovascular disease. 7.Patients with moderate to severe liver dysfunction and severe renal dysfunction (creatinine clearance rate less than 30 ml/min). 8.Patients with diabetes. 9.Patients with gastrointestinal motility disorders (constipation) or delayed gastric emptying diseases. 10.Patients with reflux esophagitis or bile reflux gastritis. 11.Patients with inflammatory bowel disease. 12.Pregnant or breastfeeding women. 13.Patients with mental disorders or limited mobility. 14.Patients deemed unsuitable for participation in this study by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rates of perforation ;The incidence of bleeding;The incidence of electrocoagulation syndrome;The incidence of postoperative infections ( intraincluding-abdominal infections) ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of thirst;The incidence of hunger;The incidence of dry mouth;The incidence of postoperative nausea;The incidence of postoperative vomiting;The incidence of abdominal pain;The VAS score for abdominal pain;The time of first flatus;Hospitalization costs; | — |
Countries
China
Contacts
General Hospital of Northern Theater Command