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SNARE family proteins regulate keratinocyte-neuron signal transduction in rosacea

SNARE family proteins regulate keratinocyte-neuron signal transduction in rosacea

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104151
Enrollment
Unknown
Registered
2025-06-11
Start date
2025-06-23
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rosacea

Interventions

Normal group:none
Case group:none

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Rosacea trial group inclusion criteria: rosacea was clinically considered but pathological biopsy was needed to confirm the diagnosis; 18-50 years old; Informed consent was obtained voluntarily. 2.The inclusion criteria of normal control group were as follows: midfacial benign skin tumor requiring surgical resection; 18-50 years old; Those who voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Pregnancy and lactation; 2.Use of topical antibiotics or tretinoin within 1 month Preparations, immunosuppressants, and glucocorticoids; 3.patients who had received vascular laser treatment within 1 month Such as flash pump pulsed dye laser and intense pulsed light; 4.other allergic or inflammatory diseases, e.g Acne, Seborrheic dermatitis, Atopic dermatitis, Contact dermatitis, Photosensitive dermatitis, Hormone-dependent dermatitis, Lupus erythematosus, skin tumors, etc., which may affect the experimental results; 5.cardiovascular and cerebrovascular diseases, liver, kidney and hematopoiesis Systemic and other serious diseases or mental type diseases.

Design outcomes

Primary

MeasureTime frame
immumohistochemical staining of SNARE family proteins;

Secondary

MeasureTime frame
polymerase chain reaction Detection of SNARE Family Protein Gene Expression;

Countries

China

Contacts

Public ContactWu Lin

Peking University Shenzhen Hospital

119544648@qq.com+86 13510169619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026