rosacea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Rosacea trial group inclusion criteria: rosacea was clinically considered but pathological biopsy was needed to confirm the diagnosis; 18-50 years old; Informed consent was obtained voluntarily. 2.The inclusion criteria of normal control group were as follows: midfacial benign skin tumor requiring surgical resection; 18-50 years old; Those who voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pregnancy and lactation; 2.Use of topical antibiotics or tretinoin within 1 month Preparations, immunosuppressants, and glucocorticoids; 3.patients who had received vascular laser treatment within 1 month Such as flash pump pulsed dye laser and intense pulsed light; 4.other allergic or inflammatory diseases, e.g Acne, Seborrheic dermatitis, Atopic dermatitis, Contact dermatitis, Photosensitive dermatitis, Hormone-dependent dermatitis, Lupus erythematosus, skin tumors, etc., which may affect the experimental results; 5.cardiovascular and cerebrovascular diseases, liver, kidney and hematopoiesis Systemic and other serious diseases or mental type diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| immumohistochemical staining of SNARE family proteins; | — |
Secondary
| Measure | Time frame |
|---|---|
| polymerase chain reaction Detection of SNARE Family Protein Gene Expression; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital