Lung nodules
Conditions
Interventions
Gold Standard:Clinical pathology examination
Index test:Imageomics-based automatic recognition combined with multi-omics and liquid biopsy for diagnosis
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Subjects with pulmonary nodules, including benign nodules/pure ground-glass nodules (pGGN)/part-solid nodules (mGGN)/solid nodules; 2. Surgical or biopsy tissue specimens with pathological confirmation; 3. Pulmonary nodule diameter = 18 years; 5. Complete clinical records and clear diagnosis; 6. Willingness to sign informed consent;
Exclusion criteria
Exclusion criteria: 1. Patients with other malignancies occurring within the past 3 years; 2. Unresectable surgery (except benign nodules); 3. Patients with other treatments such as neoadjuvant therapy before surgery; 4. Patients with HIV, HBV, HCV, syphilis and other infections; 5. Patients without preoperative blood specimens or with unacceptable preoperative blood specimens. 6. History of allogeneic blood transfusion within six months prior to surgery. 7. Pregnant or lactating women; 8. History of bone marrow transplantation or cell transplantation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity;Clinical Impact Curve, CIC;Sensitivity;Clinical Decision Curve Analysis, DCA;Receiver Operating Characteristic curve; | — |
Countries
China
Contacts
Public ContactJigang Dai
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed