Acute Decompensated Heart Failure
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years, gender is not limited; 2. Hospitalized patients with clinical diagnosis of acute decompensated heart failure, among which the diagnosis time of patients with acute decompensated heart failure is no more than 48 hours when using recombinant human brain natriuretic peptide; 3. Patients presenting at the target center with recombinant human brain natriuretic peptide >=72 hours; 4. NYHA Cardiac Function Grading III.~IV. (refer to the Cardiac Function Grading of the New York College of Cardiology); 5. NT-proBNP>300pg/ml.
Exclusion criteria
Exclusion criteria: 1. Those with cardiogenic shock, systolic blood pressure <90mmHg, severe valvular stenosis/obstructive cardiomyopathy, or uncontrolled malignant arrhythmia; 2. Those with severe liver or kidney dysfunction; 3. Cases that researchers believe affect the evaluation of the investigated drug and are not suitable for collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-terminal Pro-B-type Natriuretic Peptide, NT-proBNP;Urine volume;B-type Natriuretic Peptide, BNP;Body weight;Remission rate of dyspnea;Edema improvement rate;The improvement rate of pulmonary rales; | — |
Countries
China
Contacts
Public ContactYugang Dong
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed