Stroke
Conditions
Interventions
Experimental group:Intermittent oral feeding to the esophageal feeding tube
Control Group:Nasogastric Tube (NGT)
Sponsors
Mianyang Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Time from stroke onset to randomization = Grade 3; 5.Requirement for enteral nutrition support; 6.Written informed consent provided by the patient or legal guardian.
Exclusion criteria
Exclusion criteria: 1.Intracranial hemorrhage confirmed by CT/MRI; 2.History of prior stroke with residual dysphagia (Grade >=3); 3.Pharyngeal or esophageal tumors; 4.Obstruction of the mid-to-lower esophagus; 5.Contraindications to enteral nutrition (e.g., intestinal ischemia, perforation); 6.Thoracic aortic aneurysm; 7.Acute respiratory distress syndrome (ARDS); 8.History of gastrointestinal perforation; 9.Anatomical deformities of the pharynx or cervical region; 10.Severe cognitive impairment precluding cooperation; 11.Coagulopathy (INR >1.5 or platelet count <50×10?/L); 12.Nasal obstruction preventing nasogastric tube placement; 13.History of corrosive substance ingestion; 14.Active gastrointestinal bleeding; 15.Concurrent participation in other interventional trials; 16.Pre-existing gastrostomy or nasogastric tube prior to stroke onset; 17.Life expectancy <6 months due to terminal illness; 18.Anticipated inability to complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Mass Index (BMI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional Status;EuroQol Five-Dimensional Questionnaire (EQ-5D) Score;National Institutes of Health Stroke Scale (NIHSS) Score;Swallowing Function;Incidence of Stroke-Associated Pneumonia (SAP);Modified Rankin Scale (mRS) Score; | — |
Countries
China
Contacts
Public ContactLuo Min
Mianyang Central Hospital
Outcome results
None listed