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Clinical Study of Phage Therapy for Multidrug-Resistant Organism Pneumonia in the Intensive Care Unit

Clinical Study of Phage Therapy for Multidrug-Resistant Organism Pneumonia in the Intensive Care Unit

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104137
Enrollment
Unknown
Registered
2025-06-11
Start date
2025-06-13
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug-resistant bacterial infection

Interventions

Phage therapy group:Nebulized inhaled phage for the treatment of drug-resistant bacterial infections

Sponsors

Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 95 Years

Inclusion criteria

Inclusion criteria: (1) Patients 18-95 years of age with multiple drug-attached bacterial infections of the lungs who are unable to benefit from treatment except for tumors and other end-stage diseases (based on the results of drug sensitivity testing at our institution); (2) Drug-resistant bacteria are sensitive to phage; (3) Subjects and family members (or guardians) fully read, understood and signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Bacterial infections can be effectively controlled by antibiotic therapy; (2) Local administration to the respiratory tract cannot be performed; (3) Exceeding the unit's medical service load; (4) Thinkers who are judged by the investigator to be unsuitable for participation in this study.

Design outcomes

Primary

MeasureTime frame
Laboratory Judgment Criteria;Clinical judgment criteria;

Secondary

MeasureTime frame
Inflammatory indicators;Security Indicators;Microbiological indicators;Imaging indicators;

Countries

China

Contacts

Public ContactLiu xueyan

Shenzhen People's Hospital

13554843721@163.com+86 180 2538 8894

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026