cardiac arrest
Conditions
Interventions
Full Brain Resuscitation Group:N/A
Neurological Functional Impairment Group:N/A
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Ages 18-75 years old; 2. Cardiac arrest with witnessed bystander; 3. Time from CA to initial CPR is less than 5 minutes; 4. Estimated time from CA to initiation of ECMO is =60 minutes; 5. No known life-limiting comorbidities (such as end-stage heart failure/COPD/end-stage renal failure/liver failure/terminal illness); 6. Informed consent form signed;
Exclusion criteria
Exclusion criteria: 1. Without Informed consent form signed; 2. Irreversible brain damage; 3. End-stage malignant disease; 4. Uncontrollable traumatic bleeding; 5. Aortic dissection with pericardial effusion; 6. Moderate to severe aortic valve regurgitation; 7. Cardiac rupture; 8. Pregnancy; 9. Deemed unsuitable for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30-day Good Neurological Survival Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to return of spontaneous circulation (ROSC);Length of ICU stay;180-day Survival Rate;Incidence of ECMO complications;90-day Survival Rate;90-day Good Neurological Survival Rate;Duration of CPR;Mechanical ventilation duration;The plasma concentration of biomarkers such as Neuron-Specific Enolase (NSE);180-day Good Neurological Survival Rate; | — |
Countries
China
Contacts
Public ContactHao Xing
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed