Postoperative Delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing kidney transplant surgery under general anesthesia at The First Affiliated Hospital of China Medical University; 2. Aged >=18 years; 3. Provided written informed consent and voluntarily agreed to participate after full explanation of the study protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with preoperative consciousness disturbance or cognitive impairment; 2. Multi-organ transplant recipients; 3. Patients unable to complete delirium assessments due to psychiatric disorders, hearing/visual impairments; 4. Chronic use of antipsychotics or benzodiazepines (>1 month) before surgery; 5. Preoperative MMSE scores below education-adjusted cutoffs (Illiterate <=17, Elementary <=20, Secondary <=22, College <=23); 6. Patients who died within 24 hours postoperatively;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium in kidney transplant recipients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Etiology of End-Stage Renal Disease (ESRD);Gender;Degree of education;End-tidal Volatile Anesthetic Concentration (ETAC);Age;Body mass index(BMI);Postoperative Pain;Long-acting Opioids for Postoperative Analgesia;Intraoperative blood loss volume;Preoperative anxiety;Duration of anesthesia;Preoperative overnight sleep status;Operation duration;Intraoperative Electrolyte Levels;Duration of dialysis (years); | — |
Countries
China
Contacts
The First Hospital of China Medical University