Diabetic retinopathy secondary to neovascular glaucoma
Conditions
Interventions
Retrospective Observation Group:No specific interventions or exposure factors are set for this study, and study participants will receive routine diabetic eye disease treatment and f
Prospective Observation Group:No specific interventions or exposure factors are set for this study, and study participants will receive routine diabetic eye disease treatment and f
Sponsors
Shenzhen Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.(Retrospective group) Age and sex: male and female patients aged 18 years and over to include a broad representation of the adult population; 2.(Retrospective group) Disease diagnosis: patients with a clinical diagnosis of diabetic retinopathy (DR) within the last 3 years, including all types of DR; 3.(Retrospective group) Medical history: with detailed medical history and sufficient medical information, including time of diabetes diagnosis, diagnosis and grading of DR, treatment history, etc. 4.(Retrospective group) Data completeness: the patient's medical record must contain complete clinical data and biomarker data sufficient to support the data analysis needs of this study; 5.(Prospective group) Age and Gender: Male and female patients aged 18 years or older, with no upper limit, to ensure broad representation of the adult population. 6.(Prospective group) Diagnosis: Patients clinically diagnosed with diabetic retinopathy (DR) by ophthalmologists, including both non-proliferative and proliferative DR. 7.(Prospective group) Duration of Diabetes: A confirmed diagnosis of diabetes for at least 5 years is required, accounting for the long-term effects of diabetes on the progression of ocular complications. 8.(Prospective group) Informed Consent: Participants must demonstrate comprehension of the study and voluntarily sign the informed consent form, indicating their agreement to participate and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1.(Retrospective group) Other Ocular Conditions: Presence of significant ocular comorbidities (e.g., uncontrolled glaucoma, severe dry eye syndrome) that may confound the study outcome assessments. 2.(Retrospective group) Recent eye surgery: eye surgery or specific treatment (e.g., anti-VEGF treatment) within 6 months prior to inclusion, which may interfere with the risk assessment of NVG. 3.(Retrospective group) Incomplete medical records: patients lacking sufficient clinical data or with incomplete medical record information will be excluded to ensure the accuracy of data analysis. 4.(Retrospective group) Serious systemic diseases: suffering from serious systemic diseases, such as end-stage renal disease and heart disease, which may affect the overall health status of patients and the interpretation of study data. 5.(Prospective group) Other eye diseases: Pre-existing severe congenital eye diseases or other eye diseases (e.g., severe dry eye, keratoconus, etc.), which may interfere with the assessment of DR and NVG. 6.(Prospective group) Recent Ocular Surgery: Having undergone ocular surgery or specialized ocular treatments within the past 6 months, as these interventions may affect the risk assessment of NVG. 7.(Prospective group) Systemic Diseases: Presence of significant systemic comorbidities (e.g., end-stage renal disease, uncontrolled hypertension, or cardiac disease) that may adversely affect the patient's overall health status and ability to participate in the study. 8.(Prospective group) Inability to Complete Follow-up: Patients who cannot guarantee at least 1 year of follow-up or are at high risk of being lost to follow-up will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| whether Blood Parameters affects the incidence of NVG;Incidence and associated risk factors of NVG; | — |
Secondary
| Measure | Time frame |
|---|---|
| whether Optical Coherence Tomography (OCT) Data affects the incidence of NVG;whether Corneal Endothelial Cell Count affects the incidence of NVG;whether Medical History and Patient Demographic Data affects the incidence of NVG;whether Ocular Biometric Parameters affects the incidence of NVG; | — |
Countries
China
Contacts
Public ContactZhichao Yan
Shenzhen Eye Hospital
Outcome results
None listed