Ischemic left ventricular systolic dysfunction,Coronary artery disease
Conditions
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Men and women >= 18 years old; 2.LVEF = 70% based on coronary angiography, fractional flow reserve (FFR) 50% based on coronary angiography, intravascular ultrasound (IVUS) minimum luminal area [MLA] value <= 6.0 mm2 (< 4.5 mm2 Asian descent), or equivalent optical coherence tomography (OCT) measurements. 4.Planned CABG or PCI within 3 months.
Exclusion criteria
Exclusion criteria: 1.Concomitant valve disease or other condition (e.g., LV aneurysm) requiring surgical repair or replacement; 2.Contraindication to CMR (i.e. magnetically activated materials), gadolinium (known or suspected hypersensitivity, glomerular filtration rate = 50%] disease]); 3.Active neoplasm and/or severe end-organ dysfunction (e.g. end-stage renal disease, liver or respiratory failure) with expected life expectancy less than 5 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| viability indices; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major adverse cardiovascular events (all cause death, stroke, spontaneous MI, unplanned RR, or HF readmission); | — |
Countries
China
Contacts
Public ContactQiang Zhao
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed