Gallstones or cholecystitis
Conditions
Interventions
Experimental group:Remazolam toluenesulfonate group for injection: Induction of anesthesia: Intravenous injection of remazolam toluenesulfonate 0.2 mg/kg, Sufentanil citrate injection 0.3µg/kg and roc
Control group:Propofol emulsion injection: Anesthetic induction: Propofol emulsion injection 2 mg/kg, Sufentanil citrate injection 0.3µg/kg and rocuronium bromide injection 0.8mg/kg were injected intr
Sponsors
Jintang County first People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1, 18<= age < 60 years old, gender is not limited; 2. A clear diagnosis requires elective laparoscopic cholecystectomy (LC) treatment. 3. No cognitive behavior disorder; 4, ASA II or III, the expected time of surgery is less than 2 hours; 5. Voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to drugs used in this study; 2. People with mental or nervous system diseases; 3. People who are dependent on or tolerant to opioids; 4, serious cardiovascular system, respiratory system, liver and kidney diseases; 5. Participated in or is participating in other drug clinical trials within the last 3 months; 6. Pregnant or lactating women; 7. Those who are not considered suitable for inclusion by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to reach the goal of sedation;Subject's sedation and recovery time;RASS sedative agitation score;MAP,HR,BIS,SPO2;CRP, C-reactive protein; | — |
Countries
China
Contacts
Public ContactLi Deyuan
First People's Hospital of Jintang County, Sichuan Province
Outcome results
None listed