Colorectal polyp
Conditions
Interventions
Group A:The trial drug mannitol solution was administered orally before surgery
Group B:The control drug compound polyethylene glycol electrolyte powder was taken orally before surgery
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Participants aged between 18 and 80 years; 2.One or more non-cancerous colorectal polyps with a diameter of < 10mm were diagnosed preoperatively, and cold resection of colorectal polyps was planned in each research center; 3.Voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to the investigational drug and its components; 2. Participants with any polyp removed by HSP and/or EMR; 3. Participating in other clinical trials or receiving special drug treatment; 4. Known or suspected gastrointestinal bleeding, gastrointestinal perforation or gastrointestinal obstruction; 5. Ascites, suspicious electrolyte abnormalities or uncorrected dehydration; 6. Presence or high suspicion of colorectal cancer, inflammatory bowel disease, toxic colitis or toxic megacolon; 7. Previous colorectal resection; 8. Known severe renal insufficiency, severe hepatic insufficiency, or severe congestive heart failure; participants with severe cardio-cerebrovascular, metabolic, endocrine and other diseases could not tolerate the examination; 10. (Prepare) pregnant or lactating women; 11. Constipation (defecation frequency <3 times per week, difficult and laborious defecation, dry stool, less volume, and more than 3 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Qualification rate of intestinal preparation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Security (eg. Adverse reactions of bowel cleansing solution, Incidence of adverse events related to cold resection);Acceptability;Obedience (including indicators such as the proportion of patients who ingested the bowel preparation agent and the proportion who successfully completed bowel preparation);Cecal intubation rate;Colonoscopy procedure time; | — |
Countries
China
Contacts
Public ContactBing Hu
West China Hospital, Sichuan University
Outcome results
None listed