Postoperative cognitive decline
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients scheduled for elective CEA under general anesthesia 2.Age >= 60 years 3.ASA physical status I–III 4.No dementia 5.No severe hearing/visual impairment, language disorder, or communication difficulties. 6.Not concurrently participating in other clinical trials 7.Willing to participate in this study
Exclusion criteria
Exclusion criteria: 1.Abnormal Activities of Daily Living (ADL) score 2.Alcohol or drug dependence 3.Cognitive impairment caused by other conditions (e.g., traumatic brain injury, neurodegenerative diseases, etc.) 4.Patients with severe comorbidities (e.g., major cardiovascular, hepatic, renal, or hematologic diseases) or a history of delirium/psychiatric disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Delirium;Postoperative pain intensity; | — |
Countries
China
Contacts
Peking University Third Hospital