Moderate to severe cancer pain
Conditions
Interventions
Control group:Titration was carried out using morphine hydrochloride tablets alone
Experimental group:Hydromorphine hydrochloride sustained-release tablets were added on the basis of the control group
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient meets the diagnostic criteria for moderate to severe cancer pain in the "Diagnosis and Treatment Specifications for Cancer Pain". 2. The patient has no tolerance to opioid drugs; 3. During the entire period of this therapeutic effect evaluation, the patient did not undergo radiotherapy or chemotherapy. 4. The patient is expected to survive for more than two months.
Exclusion criteria
Exclusion criteria: 1. Exclude those with severe functional disorders of organs such as the heart; 2. Exclude those with contraindications to opioid drugs such as headache, respiratory depression or paralytic intestinal obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain relief situation; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality;Adverse reactions; | — |
Countries
China
Contacts
Public ContactFeng Xiaobo
Zhongnan Hospital, Wuhan University
Outcome results
None listed