None
Conditions
Interventions
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Signed written informed consent; 3.Patients requiring rapid oral induction of tracheal intubation;
Exclusion criteria
Exclusion criteria: 1.Patients unsuitable for rapid sequence induction intubation; 2.Patients with known hypersensitivity to etomidate and esketamine; 3.Patients with cardiogenic shock; 4.Patients with known hypersensitivity to etomidate and ketamine; 5.Hypertension (SBP >=140 mmHg) before intubation; 6.Heart rate >=140 beats/minute before intubation; 7.Clinicians believe that induction medications other than ketamine or etomidate are needed to provide optimal treatment for the patient; 8.Informed consent cannot be obtained from the patient or guardian; 9.Previously enrolled patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure, MAP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of other hemodynamic indexes during the peri-intubation period;Intubation-related adverse events;Mortality;7-Day mortality; | — |
Countries
China
Contacts
Public ContactZhang Sheng
Peking University Shenzhen Hospital
Outcome results
None listed