Post-Traumatic Stress Disorder
Conditions
Interventions
Experimental group:Ultrasound-guided stellate ganglion block before anesthesia
Control group:Sham stellate ganglion block treatment with normal saline injection before anesthesia
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Pathologically confirmed gastrointestinal malignant tumors (stages I–III),Age: 18–75 years old;KPS score >=70; 2.Posttraumatic Stress Disorder Checklist for Civilian (PCL-C) score >=38; 3.Stable dosage of psychotropic medications for >=3 months (if applicable); 4.Adequate ability to use electronic follow-up devices.
Exclusion criteria
Exclusion criteria: 1.Patients who refuse to participate in this study; 2.Patients with a history of allergy to amide-type local anesthetics; 3.Pregnant or lactating patients; 4.Patients with contraindications to stellate ganglion block (SGB), including: Coagulation dysfunction (INR > 1.5–2.0, APTT > 1.5–2.0 times the upper limit of the normal range) Local skin ulceration or infection Severe chronic obstructive pulmonary disease (COPD) Acute myocardial infarction Glaucoma, etc. 5.Patients with anatomical abnormalities, such as: Congenital cervical spine malformations (e.g., cervical fusion, vertebral dysplasia) History of neck surgery or trauma causing altered anatomical structures Neck tumors involving the vicinity of the stellate ganglion 6.Patients who have previously received SGB treatment; 7.Patients who showed no response to stellate ganglion block therapy; 8.Patients with schizophrenia or other mental disorders affecting SGB procedures and subsequent evaluations; 9.Patients with moderate to severe traumatic brain injury; 10.Patients with symptoms of moderate to severe substance use disorder within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CAPS-5 total symptom severity score from baseline to 6 months post-treatment;Social function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depressive symptoms;Anxiety symptoms;Quality of life;Sleep quality;Pain symptoms;Cognitive function; | — |
Countries
China
Contacts
Public ContactQun Lin
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed