Hirschsprung disease
Conditions
Interventions
Gold Standard:Pathologic gold standard of transition zone:(1) complete absence of ganglion cells of a segment equal to >1/8 of the circumference in the submucosal and/or myenteric plexuses (2) a segm
Index test:Based on the intraoperative rapid pathological grading system for congenital Hirschsprung disease used at our institution, the slides were classified into six categories according to the as
Sponsors
Xinhua Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with histopathologically confirmed Hirchsprung Disease, including short-segment HSCR, long-segment HSCR and total colon aganglionosis. 2. Complete clinical data and pathological information; 3. Patients who signed written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. The pathologic diagnosis is intestinal neuronl dysplasia; 2. The pathologic diagnosis is chronic intestinal pesudo-obstruction. 3. Combined with chromosomal abnormalities and other congenital disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the area under the receiver operating characteristic (AUC);Accuracy;Sensitivity;Specificity;Positive predictive values;Negative predictive values;Kappa; | — |
Countries
China
Contacts
Public ContactZhang Minzhong
Xinhua Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed