Hemodialysis cognitive impairment
Conditions
Interventions
Blood Purification Therapy Group:hemodialysis
Non-Dialysis CKD Group:Non-Dialysis CKD
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for the Blood Purification Therapy Group:?? 1)Patients receiving maintenance hemodialysis; 2)Availability of complete demographic data and partial biochemical parameters (including age, sex, comorbidities, and educational attainment); 3)Willingness to provide written informed consent. ?? 2. Inclusion Criteria for the Non-Dialysis CKD Group:?? 1)Patients with stage 4-5 chronic kidney disease (CKD) not requiring dialysis, with an estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m²; 2)Availability of complete demographic data and partial biochemical parameters (including age, sex, comorbidities, and educational attainment); 3)Willingness to provide written informed consent.
Exclusion criteria
Exclusion criteria: ?1. Exclusion Criteria for the Blood Purification Therapy Group:?? 1)Patients with severe infections, malignancies, or severe cardiovascular diseases; 2)Patients unable to cooperate with hemodialysis-related cognitive function assessments; 3)Hemodialysis patients with comorbid conditions that may interfere with cognitive assessment (including intracranial tumors, traumatic brain injury, recent stroke, visual or hearing impairments); 4)Patients unwilling to undergo follow-up evaluations; 5)Other circumstances deemed by investigators as unsuitable for study participation. ?? 2. Exclusion Criteria for the Non-Dialysis CKD Group:?? 1)Patients with severe infections, malignancies, or severe cardiovascular diseases; 2)Patients unable to cooperate with cognitive function assessments; 3)Patients with comorbid conditions that may interfere with cognitive assessment (including intracranial tumors, traumatic brain injury, recent stroke, visual or hearing impairments); 4)Patients unwilling to undergo follow-up evaluations; 5)Other circumstances deemed by investigators as unsuitable for study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function;Cognitive function; | — |
Countries
China
Contacts
Public ContactChen Jing, Qian Jing
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed