Subjective Cognitive Decline, SCD
Conditions
Interventions
Test group:VR cognitive training (HTC Vive Pro) 30 minutes per session, 5 sessions per week × 4 weeks
Control group:Standard care plan for Alzheimers disease (including adjusting dietary structure and adopting a Mediterranean diet
controlling risk factors for cognitive decline, such as reducing sedentary behavior, increasing exercise and social interaction
paying attention to emotions and how to adjust them
and controlling underlying conditions such as hypertension, diabetes, and hyperlipidemia)
Sponsors
Rehabilitation Medical Center of Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 55–80 years old; (2) Primary school education or above, no visual or hearing impairments, able to cooperate in completing the assessment; (3) Overall cognitive function assessment: MOCA >= 26 points and SCD-Q9 >= 5 points; (4) Voluntarily participate in this study and sign an informed consent form .
Exclusion criteria
Exclusion criteria: (1) History of neuropsychiatric disorders, such as cerebrovascular disease, depression, schizophrenia, substance dependence, intracranial tumors, refractory epilepsy, Parkinson's disease, normal pressure hydrocephalus, brain tumors, and cranial trauma surgery; (2) Severe diseases of the heart, liver, kidneys, hematopoietic system, or endocrine system that significantly impair cognitive function; (3) MRI findings of cerebral infarction lesions, microbleeds, or space-occupying lesions; (4) Currently undergoing other non-pharmacological interventions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function;Specific cognitive domain (memory function);Specific cognitive domain (executive function);Specific cognitive domain (naming function);Activities of daily living;Imaging acquisition;Physiological data signal acquisition;Eye movement data acquisition ;Functional near-infrared device assessment; | — |
Countries
China
Contacts
Public ContactZhu Yi
The First Affiliated Hospital of Nanjing Medical University, School of Nursing
Outcome results
None listed