postoperative recovery quality
Conditions
Interventions
Control group (Group C):Intravenous injection of propofol
Experimental group (F group):Intravenous injection of fospropofol
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age range: 18-75 years old, gender not limited; (2) American Society of Anesthesiologists (ASA): Grades I-III; (3) Body Mass Index (BMI): 18.5-30 kg/m2; (4) Selective abdominal surgery is required under general anesthesia, with an estimated surgery time of 1-3 hours; (5) I voluntarily participated and signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with contraindications to general anesthesia or a history of anesthesia accidents; (2) Patients with combined traumatic brain injury, intracranial hypertension, stroke, unstable angina, and myocardial infarction; (3) Respiratory insufficiency, obstructive pulmonary disease, presence of difficult airways, or difficulty in endotracheal intubation (modified Mahalanobis score III or IV) (4) Uncontrolled diabetes or hypertension; (5) History of drug use, alcohol abuse, or drug dependence; (6) Abuse or long-term use of anesthetics, sedatives, and analgesics; (7) Individuals who are known or suspected to be allergic or contraindicated to the various components of the investigational drug or the standardized use of drugs specified in the protocol (such as sufentanil citrate injection, propofol medium/long-chain fat emulsion, remifentanil hydrochloride injection, and propofol disodium injection); (8) Individuals with a history of mental illness; (9) Individuals who have participated in any drug clinical trials within the past month prior to screening; (10) The researchers believe that there are any other factors that are not suitable for participants in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery quality within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery quality within 48 hours after surgery;Recovery quality within 72 hours after surgery;Quality evaluation of anesthesia recovery in PACU;Changes in hemodynamic indicators;postoperative side reactions; | — |
Countries
China
Contacts
Public ContactLiwei Wang
Xuzhou Central Hospital
Outcome results
None listed