prolonged disorders of consciousness
Conditions
Interventions
Prospective Study Section:NA
Sponsors
The Third Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Aged 1-18 years, regardless of sex; (2) Diagnosed with pediatric disorders of consciousness (pDoC) and classified into vegetative state/unresponsive wakefulness syndrome (VS/UWS) or minimally conscious state (MCS) based on established diagnostic criteria; (3) Availability of complete clinical Coma Recovery Scale-Revised (CRS-R) assessment records.
Exclusion criteria
Exclusion criteria: (1) Documented history of genetic diseases, congenital metabolic disorders, tumors, or pre-existing brain injuries; (2) Presence of pre-existing developmental disorders prior to the onset of the disorder; (3) Incomplete clinical or assessment records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Age;Gender;etiology;Length of illness at admission;Time since injury to altered state of consciousness;Coma Recovery Scale-Revised; | — |
Secondary
| Measure | Time frame |
|---|---|
| electroencephalogram;Brainstem auditory evoked potential;Visual evoked potential (VEP);somatosensory evoked potential;Structural Brain Magnetic Resonance Imagin;Diffusion Tensor Imaging;Functional Near-Infrared Spectroscopy Imaging;The ages of both parents;The educational levels of both parents;Epilepsy (Seizure Type);Paroxysmal Sympathetic Hyperactivity Syndrome;Sleep disorders; Respiratory tract infection;Malnutrition;Arousal-promoting drugs;Antiepileptic drugs;Neuroregulatory therapy;Hyperbaric oxygen; | — |
Countries
China
Contacts
Public ContactDengna Zhu
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed