Total knee replacement anemia
Conditions
Interventions
Group A:EPO 10000IU qd
Group B:EPO 10000IU qod
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18~80 who meet the diagnostic criteria for osteoarthritis of the American College of Rheumatology and undergo primary total knee arthroplasty due to end-stage osteoarthritis; 2. Hemoglobin <=130 g/L before the first dose of study treatment 3. Those who have good compliance, are willing and able to conduct follow-up observation and sign informed consent as required;
Exclusion criteria
Exclusion criteria: 1. Patients who received a large number of blood within 3 months before the first administration of the study therapy (transfused more than 3 units of red cell suspension); 2. History of deep venous thromboembolism; 3. Have a history of EPO use allergy; 4. Patients who do not want to participate in this study and do not sign informed consent; 5. Poor compliance, unable to cooperate with the critical time follow-up observers; 6. For any reason, the researcher considers it impossible for the subject to complete the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion volume;Blood transfusion rate; | — |
Countries
China
Contacts
Public ContactZhao Ran
Peking University Third Hospital
Outcome results
None listed