Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Conditions
Interventions
Observation group:None
Sponsors
Zhongshan Hospital Affiliated to Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age>=18 years. 2. Diagnosed malignant tumor (any tumor type, stage, excluding patients in the palliative treatment period) and have not been treated with platinum-based or taxane-based (or combined) chemotherapy. 3. Karnofsky index of general health assessed by the Karnofsky index of the Karnofsky index of the Kar>nofsky functional status rating scale. 4. Predicted survival at screening>=12 weeks, and can receive treatment with current anti-tumor regimen for at least 1 cycle or more. 5. Voluntarily join this study, sign the informed consent form, and have good compliance.
Exclusion criteria
Exclusion criteria: 1.Prior chemotherapy with platinum-based agents or taxanes (or combinations). 2.Use of neurotoxic medications (non-chemotherapy agents) within 3 months before study initiation or current use. 3.Pre-existing peripheral neuropathy before study enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of CIPN;CIPN scale score;serum exosome; | — |
Countries
China
Contacts
Public ContactLi Xiao
Zhongshan Hospital Affiliated to Xiamen University
Outcome results
None listed