myopia
Conditions
Interventions
ICL surgery high myopia group:NA
ICL surgery ultra-high myopia group:NA
SMILE operation low myopia group:NA
ICL operation low to moderate myopia group:NA
SMILE operation group of moderate myopia:NA
SMILE operation group of high myopia:NA
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. The patient fully understands the purpose and risks of the proposed surgery, is willing to undergo the surgery, and has reasonable expectations for the surgery. 2. Subjects who have signed the informed consent for donation of biological samples and health-related information upon admission. 3. Age range: 18 to 50 years old. 4. Refractive power change within two years = 0.50D; preoperative spherical equivalent = -10.00D, astigmatism = -5.00D; 5. Best corrected distance visual acuity (CDVA) =20/25. 6. Patients who were planned to undergo SMILE had a preoperative corneal stromal thickness of =470 µm. Patients with moderate to high ectasia risk scores (score =3) according to the Randleman ectasia risk score. 7. The estimated residual stromal bed thickness (RST) of patients who are scheduled to undergo SMILE after lens removal is =270 µm. 8. Stop wearing soft contact lenses for at least 1 week, hard contact lenses for at least 3 weeks, and orthokeratology lenses for at least 3 months. 9. Other ocular diseases and/or systemic organic diseases that may affect surgical recovery. 10. Patients who are planning to undergo ICL have anterior chamber depth =2.80mm, corneal endothelial count =2000/mm2, open angle, stable corneal morphology, no progressive opacity of the lens, no proliferative lesions in the vitreous body, and no active lesions in the macula and peripheral retina.
Exclusion criteria
Exclusion criteria: 1. Suffering from other eye diseases: keratoconus or suspected keratoconus, active keratoconjunctivitis, severe dry eyes, glaucoma, active eye lesions or infections, severe ocular adnexal lesions, cataracts that seriously affect vision, severe fundus diseases, etc. 2. Obvious corneal scars or lens opacities may affect observation. 3. Active systemic inflammation, connective tissue disease, autoimmune disease, or other systemic disease or mental illness that makes it impossible to cooperate with surgery. 4. There is a history of previous eye surgery. 5. Are menstruating, pregnant, or breastfeeding. 6. Those who are allergic to the ingredients of surgical drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| dsDNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| METs markers MPO, MCP1, inflammatory factors; | — |
Countries
China
Contacts
Public ContactJinhui Dai
Zhongshan Hospital, Fudan University
Outcome results
None listed